Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514464 | 0.96 | PLA2G2A (0.64) | PLA2G2APDE10AKDM4ENPC1ALDH1A1 | |
| SCHEMBL28516151 | 0.88 | DHODH (0.64) | PLA2G2AKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28507324 | 0.83 | TLR8 (0.46) | PLA2G2APDE10AKDM4ENPC1ALDH1A1 | |
| SCHEMBL28516072 | 0.82 | DHODH (0.61) | KDM4EALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL28521021 | 0.81 | ITGB1 (0.46) | PLA2G2ASMN1; SMN2MAPTHPGDTLR8 | |
| SCHEMBL28513286 | 0.81 | ITGB1 (0.46) | PLA2G2ASMN1; SMN2MAPTHPGDTLR8 | |
| SCHEMBL28516032 | 0.81 | TLR8 (0.56) | KDM4EALDH1A1HPGDACHETLR8 | |
| SCHEMBL28505993 | 0.80 | ACHE (0.63) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28506567 | 0.79 | KDM4E (0.71) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27990887 | 0.78 | NPC1 (0.92) | PLA2G2APDE10AKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250142-B | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2021-01-26 | — | — | CN | disclosed |