Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514197 | 1.00 | MEN1 (0.42) | MEN1KMT2ATSHRMAPK1ACHE | |
| SCHEMBL1065814 | 1.00 | MEN1 (0.42) | MEN1KMT2ATSHRMAPK1ACHE | |
| SCHEMBL28512894 | 0.90 | MEN1 (0.47) | MEN1KMT2ATSHRACHETHRB | |
| SCHEMBL19746383 | 0.89 | CYP4F2 (0.41) | MEN1KMT2ATSHRACHETHRB | |
| SCHEMBL17660228 | 0.88 | ACHE (0.47) | TSHRMAPK1ACHEALDH1A1 | |
| SCHEMBL21404617 | 0.85 | MEN1 (0.39) | MEN1KMT2ATSHRMAPK1ACHE | |
| SCHEMBL27880456 | 0.85 | ABCB11 (0.36) | TSHRACHEALDH1A1EPHX2TP53 | |
| SCHEMBL29308970 | 0.85 | ABCB11 (0.36) | TSHRACHEALDH1A1EPHX2TP53 | |
| SCHEMBL23913175 | 0.83 | ACHE (0.32) | TSHRACHEALDH1A1TP53HIF1A | |
| SCHEMBL31425438 | 0.83 | ACHE (0.32) | TSHRACHEALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |