Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | DHFR | P00374 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21515134 | 0.97 | KDM4E (0.50) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28516903 | 0.92 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21515131 | 0.89 | L3MBTL1 (0.49) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21515060 | 0.88 | L3MBTL1 (0.48) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21515185 | 0.85 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30387503 | 0.85 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28501774 | 0.80 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23005252 | 0.79 | FPR2 (0.63) | KDM4EHPGDFPR2 | |
| SCHEMBL23005249 | 0.79 | FPR2 (0.63) | KDM4EHPGDFPR2 | |
| SCHEMBL21515049 | 0.79 | L3MBTL1 (0.55) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218858-A | 2, 6-diamino-3, 4-dihydropyrimidin-4-one derivatives and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2021-01-12 | — | — | CN | disclosed |