Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133420 | 0.97 | — | — | |
| Water SCHEMBL8185638 | 0.94 | PLA2G1B (0.34) | PLA2G1BPLA2G2ATSHRNPY1RNPY2R | |
| Hydrochloric Acid SCHEMBL2243173 | 0.94 | L3MBTL1 (0.37) | PLA2G1BPLA2G2ATSHRNPY1RNPY2R | |
| Iodide SCHEMBL28522449 | 0.94 | PLA2G1B (0.34) | PLA2G1BPLA2G2ATSHRNPY1RNPY2R | |
| SCHEMBL16597197 | 0.80 | PLA2G1B (0.37) | PLA2G1BPLA2G2ATSHRNPY1RNPY2R | |
| SCHEMBL1147342 | 0.78 | TSHR (0.44) | PLA2G1BPLA2G2ATSHRNPY1RNPY2R | |
| SCHEMBL1726014 | 0.75 | — | — | |
| SCHEMBL25349886 | 0.75 | CA1 (0.33) | L3MBTL1 | |
| SCHEMBL15839414 | 0.75 | — | — | |
| SCHEMBL9637735 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341983-B | Waterborne polyurethane adhesive and preparation method thereof | 上海都昱新材料科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-112341983-A | Waterborne polyurethane adhesive and preparation method thereof | 上海都昱新材料科技有限公司 | 2021-02-09 | — | — | CN | disclosed |