Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440670 | 0.91 | HTT (0.51) | KMT2AMEN1LMNAHTTGAA | |
| SCHEMBL27947413 | 0.78 | KMT2A (0.45) | KMT2AMEN1LMNAHTTMAPK1 | |
| SCHEMBL29391544 | 0.77 | POLB (0.68) | KMT2AMEN1HTTGAAMAPT | |
| SCHEMBL709788 | 0.77 | POLB (0.68) | KMT2AMEN1HTTGAAMAPT | |
| Ammonia Solution, Strong SCHEMBL28040603 | 0.75 | POLB (0.65) | KMT2AMEN1HTTGAAMAPT | |
| Hydrochloric Acid SCHEMBL6682455 | 0.75 | POLB (0.65) | KMT2AMEN1HTTGAAMAPT | |
| SCHEMBL28409820 | 0.75 | POLB (0.65) | KMT2AMEN1HTTGAAMAPT | |
| Benzoyl Chloride SCHEMBL8174986 | 0.75 | HPGD (0.44) | KMT2AMEN1LMNAHTTGAA | |
| SCHEMBL9815789 | 0.74 | ALDH1A1 (0.52) | KMT2AMEN1LMNAMAPTRAB9A | |
| SCHEMBL29378135 | 0.74 | POLB (0.64) | KMT2AMEN1GAAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321528-A | Method for synthesizing 2-butyl-1, 2-benzisothiazolin-3-ketone | 大丰跃龙化学有限公司 | 2021-02-05 | — | — | CN | disclosed |