Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL28513507 | 0.91 | KMT2A (0.48) | HTTKMT2AGAAHPGDALDH1A1 | |
| SCHEMBL29378135 | 0.82 | POLB (0.64) | KMT2AGAAHPGDALDH1A1MEN1 | |
| SCHEMBL9815789 | 0.82 | ALDH1A1 (0.52) | KMT2AHPGDALDH1A1MEN1MAPT | |
| SCHEMBL9669181 | 0.82 | HTT (0.55) | HTTKMT2AGAAHPGDALDH1A1 | |
| SCHEMBL823696 | 0.82 | POLB (0.64) | KMT2AGAAHPGDALDH1A1MEN1 | |
| SCHEMBL27947413 | 0.82 | KMT2A (0.45) | HTTKMT2AGAAHPGDALDH1A1 | |
| SCHEMBL8533398 | 0.81 | SIRT1 (0.50) | HTTKMT2AGAAHPGDALDH1A1 | |
| SCHEMBL28858278 | 0.80 | ALDH1A1 (0.47) | HTTKMT2AGAAHPGDALDH1A1 | |
| SCHEMBL26622207 | 0.80 | HTT (0.53) | HTTKMT2AGAAHPGDALDH1A1 | |
| SCHEMBL709788 | 0.80 | POLB (0.68) | HTTKMT2AGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574472-B | Synthesis method of 1, 2-benzisothiazolin-3-ketone compound | 大连百傲化学股份有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-112624999-A | 1, 2-benzisothiazolin-3-one solid waste after-treatment process | 大丰跃龙化学有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-112321528-A | Method for synthesizing 2-butyl-1, 2-benzisothiazolin-3-ketone | 大丰跃龙化学有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-111574472-A | Synthesis method of 1, 2-benzisothiazolin-3-ketone compound | 大连百傲化学股份有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-108976248-A | A kind of hypervalent iodine compounds and its preparation method and application containing heterocycle | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2018-12-11 | — | — | CN | claimed |
| CN-103694194-A | Synthesis method of 2-methyl-1, 2-benzisothiazolin-3-ketone | SHOUGUANG SYNTECH FINE CHEMICAL CO LTD | 2014-04-02 | — | — | CN | claimed |
| CN-103664817-A | Synthesis method for 2-butyl-1, 2-benzisothiazolin-3-ketone | SHOUGUANG XINTAI FINE CHEMICAL CO LTD | 2014-03-26 | — | — | CN | claimed |
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | claimed |
| CN-118847197-A | Metal supported solid base catalyst and method for catalytic synthesis of N-butyl-1, 2-benzisothiazolin-3-one by using same | 杭州抹香鲸新材料工艺技术有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118771993-A | Method for synthesizing N-butyl-1, 2-benzisothiazolin-3-one by catalysis of alkaline ionic liquid catalyst | 杭州抹香鲸新材料工艺技术有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-107540697-B | Compound, photosensitive resin composition containing same, and color filter | 三星SDI株式会社 | 2022-05-31 | — | — | CN | disclosed |
| CN-111574472-B | Synthesis method of 1, 2-benzisothiazolin-3-ketone compound | 大连百傲化学股份有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-112624999-A | 1, 2-benzisothiazolin-3-one solid waste after-treatment process | 大丰跃龙化学有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-112624999-A | 1, 2-benzisothiazolin-3-one solid waste after-treatment process | 大丰跃龙化学有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-85109770-A | The preparation of 2-(2 '-substituted benzoyl)-hydroresorcinol compounds and as herbicide applications | — | 1987-03-04 | — | — | CN | disclosed |
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |
| US-4478837-A | HYPOTENSIVE AGENTS | SANDOZ LTD. (CH) | 1984-10-23 | — | — | US | disclosed |
| US-4014932-A | ANTHELMINTICS, PESTICIDES, MITICIDES, INSECTICIDES | THE UPJOHN COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-3954754-A | ANTIHYPERTENSIVES | SANDOZ LTD. (CH) | 1976-05-04 | — | — | US | disclosed |
| US-3931318-A | ANTHELMINTICS, PESTICIDES | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |