Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.72 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | ALPL | P05186 | 1/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | ALPG | P10696 | 1/20 | 0.61 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PHGDH | O43175 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528684 | 0.89 | SIRT1 (0.80) | KMT2AMEN1NPC1RAB9ASIRT1 | |
| SCHEMBL6568354 | 0.88 | KMT2A (0.78) | KMT2AMEN1NPC1RAB9ASIRT1 | |
| SCHEMBL6568357 | 0.88 | KMT2A (0.78) | KMT2AMEN1NPC1RAB9ASIRT1 | |
| SCHEMBL10049942 | 0.87 | SIRT1 (0.69) | KMT2AMEN1NPC1RAB9ASIRT1 | |
| SCHEMBL12746247 | 0.87 | MGAM (0.59) | KMT2AMEN1NPC1RAB9ASIRT1 | |
| SCHEMBL685583 | 0.84 | KMT2A (0.73) | KMT2AMEN1NPC1RAB9ASIRT1 | |
| SCHEMBL12746377 | 0.84 | SIRT1 (0.72) | KMT2AMEN1NPC1RAB9ASIRT1 | |
| SCHEMBL12746244 | 0.84 | KMT2A (0.77) | KMT2AMEN1NPC1RAB9ASIRT1 | |
| SCHEMBL10049701 | 0.84 | SIRT1 (0.72) | KMT2AMEN1NPC1RAB9ASIRT1 | |
| SCHEMBL6751415 | 0.84 | SIRT1 (0.72) | KMT2AMEN1NPC1RAB9ASIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | claimed |
| CN-112079744-B | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | disclosed |