Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | NPC1 | O15118 | 2/20 | 0.79 |
| ▸ | RAB9A | P51151 | 1/20 | 0.79 |
| ▸ | KDM1A | O60341 | 2/20 | 0.73 |
| ▸ | MAOA | P21397 | 1/20 | 0.73 |
| ▸ | MAOB | P27338 | 1/20 | 0.73 |
| ▸ | ALPL | P05186 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | ALPI | P09923 | 1/20 | 0.71 |
| ▸ | ALPG | P10696 | 1/20 | 0.71 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.68 |
| ▸ | GCGR | P47871 | 2/20 | 0.66 |
| ▸ | MGAM | O43451 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751418 | 0.91 | SIRT1 (0.72) | SIRT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6751415 | 0.91 | SIRT1 (0.72) | SIRT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10049701 | 0.91 | SIRT1 (0.72) | SIRT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL12746377 | 0.91 | SIRT1 (0.72) | SIRT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8343583 | 0.91 | SIRT1 (0.85) | SIRT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8343578 | 0.91 | SIRT1 (0.85) | SIRT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28517665 | 0.90 | SIRT1 (0.70) | SIRT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28519354 | 0.89 | KMT2A (0.72) | SIRT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10049942 | 0.89 | SIRT1 (0.69) | SIRT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28513871 | 0.89 | KMT2A (0.72) | SIRT1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | claimed |
| CN-112079744-B | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | disclosed |