Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 18/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28515124 | 0.89 | STING1 (0.47) | STING1 | |
| SCHEMBL28508303 | 0.86 | STING1 (0.47) | STING1 | |
| SCHEMBL22121402 | 0.84 | STING1 (0.54) | STING1 | |
| SCHEMBL28522082 | 0.84 | STING1 (0.56) | STING1 | |
| SCHEMBL19437494 | 0.80 | STING1 (0.49) | STING1 | |
| SCHEMBL19451814 | 0.79 | STING1 (0.48) | STING1 | |
| SCHEMBL19451779 | 0.79 | STING1 (0.48) | STING1 | |
| SCHEMBL28614903 | 0.79 | STING1 (0.48) | STING1 | |
| SCHEMBL19437481 | 0.77 | STING1 (0.59) | STING1 | |
| SCHEMBL22135036 | 0.77 | STING1 (0.49) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279835-B | Aromatic ring or aromatic heterocyclic imidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2022-07-22 | — | — | CN | disclosed |
| CN-112279835-A | Aromatic ring or aromatic heterocyclic imidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2021-01-29 | — | — | CN | disclosed |