Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771814 | 1.00 | AKR1C3 (0.47) | AKR1C3AKR1C1POLBMAPTCYP1B1 | |
| SCHEMBL599334 | 0.81 | AKR1C1 (0.49) | AKR1C3AKR1C1POLBMAPTKMT2A | |
| SCHEMBL599335 | 0.81 | AKR1C1 (0.49) | AKR1C3AKR1C1POLBMAPTKMT2A | |
| SCHEMBL1758233 | 0.80 | HTT (0.43) | AKR1C3AKR1C1POLBKMT2AAKR1C2 | |
| SCHEMBL1758234 | 0.80 | HTT (0.43) | AKR1C3AKR1C1POLBKMT2AAKR1C2 | |
| SCHEMBL5125335 | 0.80 | HTT (0.43) | AKR1C3AKR1C1POLBKMT2AAKR1C2 | |
| Hydrochloric Acid SCHEMBL599819 | 0.79 | AKR1C1 (0.47) | AKR1C3AKR1C1POLBMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL599818 | 0.79 | AKR1C1 (0.47) | AKR1C3AKR1C1POLBMAPTKMT2A | |
| SCHEMBL2844597 | 0.77 | MEN1 (0.49) | AKR1C3AKR1C1MAPTKMT2AMEN1 | |
| SCHEMBL3778274 | 0.77 | MEN1 (0.49) | AKR1C3AKR1C1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993123-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8993123-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8993123-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| EP-2240425-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009100925-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-08-20 | — | — | WO | disclosed |
| WO-2009100925-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, ELAVL1, EPCAM | AKR1C3 4091/4885AKR1C1 3590/4885POLB 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.