SCHEMBL2851439

SCHEMBL2851439

CCCCCCOc1ccc(I)cc1OCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 4/20 0.46
THRA P10827 2/20 0.45
THRB P10828 2/20 0.45
CHUK O15111 1/20 0.44
DAPK3 O43293 1/20 0.44
JAK2 O60674 1/20 0.44
ROCK2 O75116 1/20 0.44
PRKCG P05129 1/20 0.44
CDK1 P06493 1/20 0.44
PIM1 P11309 1/20 0.44
RPS6KB1 P23443 1/20 0.44
CDK2 P24941 1/20 0.44
AKT1 P31749 1/20 0.44
AKT2 P31751 1/20 0.44
MAPKAPK2 P49137 1/20 0.44
BLK P51451 1/20 0.44
RPS6KA3 P51812 1/20 0.44
JAK3 P52333 1/20 0.44
LIMK1 P53667 1/20 0.44
PRKCZ Q05513 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8974122 0.91 SMPD1 (0.56) SMPD1THRATHRBCHUKDAPK3
SCHEMBL8973654 0.91 THRA (0.51) SMPD1THRATHRBALDH1A1S1PR3
SCHEMBL27552799 0.89 SMPD1 (0.54) SMPD1THRATHRB
SCHEMBL27762996 0.87 THRA (0.44) SMPD1THRATHRBCHUKDAPK3
SCHEMBL28785995 0.87 THRA (0.44) SMPD1THRATHRBCHUKDAPK3
SCHEMBL27722679 0.87 THRA (0.44) SMPD1THRATHRBCHUKDAPK3
SCHEMBL9397427 0.87 PTPN11 (0.50) THRATHRBPTPN11TLR8MAPT
SCHEMBL3737253 0.86 ESR1 (0.43) SMPD1THRATHRBCHUKDAPK3
SCHEMBL8974095 0.84 ESR1 (0.49) SMPD1THRATHRBCHUKDAPK3
SCHEMBL9850738 0.84 THRA (0.51) SMPD1THRATHRBCHUKDAPK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 US disclosed
EP-1972676-B1 Liquid crystal alignment film composition, liquid crystal device and display apparatus RICOH KK (JP) 2010-03-10 EP disclosed
US-7658979-B2 Liquid crystal alignment film composition, liquid crystal device and display apparatus RICOH COMPANY, LTD. (JP) 2010-02-09 US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 US disclosed
US-20080231785-A1 LIQUID CRYSTAL ALIGNMENT FILM COMPOSITION, LIQUID CRYSTAL DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. (JP) 2008-09-25 US disclosed
EP-1972676-A1 Liquid crystal alignment film composition, liquid crystal device and display apparatus Ricoh Company, Ltd. (JP) 2008-09-24 EP disclosed
EP-0703885-A1 SYNTHESIS OF SUBSTITUTED TRIPHENYLENES, USEFUL AS DISCOTIC LIQUID CRYSTALS BRITISH TECHNOLOGY GROUP LTD (GB) 1996-04-03 EP disclosed
WO-1994029243-A1 SYNTHESIS OF SUBSTITUTED TRIPHENYLENES, USEFUL AS DISCOTIC LIQUID CRYSTALS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-12-22 WO disclosed