Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974122 | 0.93 | SMPD1 (0.56) | THRATHRBSMPD1PRSS1 | |
| SCHEMBL27552799 | 0.92 | SMPD1 (0.54) | THRATHRBSMPD1PRSS1 | |
| SCHEMBL2851439 | 0.91 | SMPD1 (0.46) | THRATHRBSMPD1S1PR2S1PR1 | |
| SCHEMBL28785995 | 0.83 | THRA (0.44) | THRATHRBSMPD1S1PR3ALDH1A1 | |
| SCHEMBL27762996 | 0.83 | THRA (0.44) | THRATHRBSMPD1S1PR3ALDH1A1 | |
| SCHEMBL8975125 | 0.83 | THRA (0.53) | THRATHRBSMPD1PRSS1S1PR2 | |
| SCHEMBL27722679 | 0.83 | THRA (0.44) | THRATHRBSMPD1S1PR3ALDH1A1 | |
| SCHEMBL11326840 | 0.81 | L3MBTL4 (0.67) | THRATHRBL3MBTL4L3MBTL3ALDH1A1 | |
| SCHEMBL19612480 | 0.81 | PLA2G4B (0.58) | THRATHRBSMPD1PRSS1PLA2G4B | |
| SCHEMBL3737253 | 0.81 | ESR1 (0.43) | THRATHRBSMPD1S1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1128985-A | Synthesis of substituted benzo [9, 10] phenanthrenes as discotic liquid crystals | BRITISH TECH GROUP CO LTD (GB) | 1996-08-14 | — | — | CN | disclosed |
| EP-0703885-A1 | SYNTHESIS OF SUBSTITUTED TRIPHENYLENES, USEFUL AS DISCOTIC LIQUID CRYSTALS | BRITISH TECHNOLOGY GROUP LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029243-A1 | SYNTHESIS OF SUBSTITUTED TRIPHENYLENES, USEFUL AS DISCOTIC LIQUID CRYSTALS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |