SCHEMBL28514599

SCHEMBL28514599

O=C(O)c1ccc(C(=O)OC(F)(F)F)cc1.[Zn]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
TP53 P04637 1/20 0.50
SRD5A2 P31213 2/20 0.47
FAAH O00519 1/20 0.45
EPHX2 P34913 1/20 0.45
ALDH1A1 P00352 4/20 0.44
HSD17B10 Q99714 1/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
RXRA P19793 2/20 0.43
RXRB P28702 2/20 0.43
RXRG P48443 2/20 0.43
CA12 O43570 1/20 0.43
CA3 P07451 1/20 0.43
TYR P14679 1/20 0.43
DRD1 P21728 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8531480 0.98 TSHR (0.52) TSHRTP53SRD5A2FAAHEPHX2
SCHEMBL29894307 0.98 TSHR (0.52) TSHRTP53SRD5A2FAAHEPHX2
Hydrochloric Acid SCHEMBL28635324 0.96 TSHR (0.50) TSHRTP53SRD5A2FAAHEPHX2
SCHEMBL28728913 0.96 TSHR (0.50) TSHRTP53SRD5A2FAAHEPHX2
SCHEMBL28391425 0.92 BCL2L1 (0.53) TSHRTP53SRD5A2FAAHEPHX2
SCHEMBL10859570 0.89 CES2 (0.41) TSHRFAAHEPHX2CA1CA2
SCHEMBL29167939 0.87 CES2 (0.39) TP53FAAHEPHX2CA1CA2
SCHEMBL11222731 0.85 TSHR (0.52) TSHRTP53SRD5A2FAAHEPHX2
SCHEMBL219676 0.83 LMNA (0.56) TSHRTP53ALDH1A1HSD17B10SMN1; SMN2
SCHEMBL28123902 0.81 LMNA (0.54) TSHRTP53ALDH1A1HSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321618-A Zinc complex with 2, 5-bis (trifluoromethyl) terephthalic acid as ligand and preparation method thereof 桂林理工大学 2021-02-05 CN claimed
CN-112321618-A Zinc complex with 2, 5-bis (trifluoromethyl) terephthalic acid as ligand and preparation method thereof 桂林理工大学 2021-02-05 CN disclosed
CN-112321618-A Zinc complex with 2, 5-bis (trifluoromethyl) terephthalic acid as ligand and preparation method thereof 桂林理工大学 2021-02-05 CN disclosed