SCHEMBL28514732

SCHEMBL28514732

Cc1c(Cl)cc(Cl)cc1Cl.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 7/20 0.45
HSD17B10 Q99714 5/20 0.45
CYP3A4 P08684 4/20 0.45
RECQL P46063 3/20 0.45
RAPGEF4 Q8WZA2 1/20 0.39
HPGD P15428 4/20 0.39
AHR P35869 2/20 0.39
TP53 P04637 2/20 0.38
HTT P42858 2/20 0.38
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
ALOX15 P16050 2/20 0.35
ALOX12 P18054 2/20 0.35
MAPK1 P28482 2/20 0.35
CASP1 P29466 2/20 0.35
CASP7 P55210 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98117 0.97 ALDH1A1 (0.53) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL1828947 0.81 RAPGEF4 (0.46) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL7729213 0.77 TSHR (0.56) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL21728879 0.77 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL10495441 0.77 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL13890701 0.77 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL4954305 0.77 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL7121407 0.77 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL5605753 0.77 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL30494020 0.77 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10CYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111989371-A Laser-platable thermoplastic composition having good flame retardancy, high thermal properties and good ductility and shaped articles made therefrom 沙特基础工业全球技术公司 2020-11-24 CN disclosed