⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2703050 | 0.75 | — | — | |
| SCHEMBL245207 | 0.75 | TSHR (0.30) | — | |
| SCHEMBL9308304 | 0.73 | — | — | |
| SCHEMBL9739895 | 0.73 | — | — | |
| SCHEMBL9739911 | 0.73 | — | — | |
| SCHEMBL28381415 | 0.73 | — | — | |
| SCHEMBL9741265 | 0.72 | — | — | |
| SCHEMBL6036462 | 0.72 | TSHR (0.30) | — | |
| SCHEMBL2848018 | 0.71 | — | — | |
| SCHEMBL9386142 | 0.71 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190071543-A1 | GELS | AORTECH BIOMATERIALS PTY LTD (AU) | 2019-03-07 | — | — | US | disclosed |
| US-9765191-B2 | Gels | AORTECH INTERNATIONAL PLC (GB) | 2017-09-19 | — | — | US | disclosed |
| US-20170121464-A1 | GELS | AORTECH BIOMATERIALS PTY LTD. (AU) | 2017-05-04 | — | — | US | disclosed |
| US-20170114187-A9 | GELS | AORTECH INTERNATIONAL PLC (GB) | 2017-04-27 | — | — | US | disclosed |
| US-20140323676-A1 | GELS | AORTECH INTERNATIONAL PLC (GB) | 2014-10-30 | — | — | US | disclosed |
| US-8623986-B2 | Gels | Aertech International plc (GB) | 2014-01-07 | — | — | US | disclosed |
| EP-2007826-B1 | GELS | AORTECH INT PLC (GB) | 2013-12-11 | — | — | EP | disclosed |
| US-20100029802-A1 | Gels | AORTECH INTERNATIONAL PLC (GB) | 2010-02-04 | — | — | US | disclosed |
| EP-2007826-A4 | GELS | AORTECH BIOMATERIALS PTY LTD (AU) | 2009-07-01 | — | — | EP | disclosed |
| EP-2007826-A1 | GELS | AorTech Biomaterials Pty Ltd (AU) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007121513-A1 | GELS | AORTECH BIOMATERIALS PTY LTD (AU) | 2007-11-01 | — | — | WO | disclosed |
| EP-1799739-A1 | GELS | AorTech Biomaterials Pty Ltd (AU) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006034547-A1 | GELS | AORTECH BIOMATERIALS PTY LTD (AU) | 2006-04-06 | — | — | WO | disclosed |