Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 2/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21201422 | 0.95 | CYP2A6 (0.43) | KDM4ECYP2A6MAPK1MEN1ALDH1A1 | |
| SCHEMBL22977642 | 0.94 | CYP2A6 (0.42) | KDM4ECYP2A6MAPK1MEN1ALDH1A1 | |
| SCHEMBL21201466 | 0.90 | ADH5 (0.52) | ADH5P4HTMPOLBHCAR2SRD5A2 | |
| SCHEMBL6252933 | 0.79 | SRD5A2 (0.59) | ADH5KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL23357794 | 0.77 | PLAU (0.46) | KDM4EMAPK1MEN1ALDH1A1MAPT | |
| SCHEMBL22554086 | 0.76 | CYP11B1 (0.51) | KDM4EMAPK1MEN1ALDH1A1MAPT | |
| SCHEMBL22977636 | 0.75 | NOTUM (0.42) | KDM4EMAPK1MEN1ALDH1A1MAPT | |
| SCHEMBL3910111 | 0.75 | EGFR (0.61) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21201361 | 0.75 | DHODH (0.48) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21201316 | 0.74 | ALPL (0.44) | POLBKDM4EALDH1A1MAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112243374-A | SREBP inhibitors comprising a 6-membered central ring | 卡普勒斯疗法有限责任公司 | 2021-01-19 | — | — | CN | disclosed |