Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | PLG | P00747 | 4/20 | 0.34 |
| ▸ | PLAU | P00749 | 4/20 | 0.34 |
| ▸ | PLAT | P00750 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16371053 | 0.90 | MAPT (0.41) | EP300RAB9ANPC1KDM4ECASP3 | |
| SCHEMBL28514795 | 0.81 | EP300 (0.43) | EP300RAB9ANPC1KDM4EHSD17B10 | |
| SCHEMBL16392463 | 0.76 | EP300 (0.57) | EP300RAB9AMEN1KMT2ABCL2 | |
| SCHEMBL24379800 | 0.76 | MEN1 (0.54) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL15956564 | 0.73 | MAPT (0.50) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL17784953 | 0.72 | EP300 (0.56) | EP300RAB9AMAPTMEN1KMT2A | |
| SCHEMBL17775416 | 0.72 | EP300 (0.48) | EP300RAB9ANPC1KDM4EMAPT | |
| SCHEMBL16371049 | 0.71 | MAPT (0.48) | EP300RAB9ANPC1KDM4EMAPT | |
| SCHEMBL17784957 | 0.70 | EP300 (0.58) | EP300RAB9ANPC1MAPTMEN1 | |
| SCHEMBL16369610 | 0.70 | EP300 (0.63) | EP300RAB9ABCL2BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793424-B | Ascomycetes amides | 亥姆霍兹感染研究中心有限公司 | 2021-02-19 | — | — | CN | disclosed |