SCHEMBL16371049

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17775442	0.91	ALDH1A1 (0.47)	MAPTGAAMAPK1NPC1RAB9A
	SCHEMBL16392463	0.91	EP300 (0.57)	GAARAB9AEP300BCL2BCL2L1
	SCHEMBL28514795	0.89	EP300 (0.43)	MAPTGAAMAPK1NPC1RAB9A
	SCHEMBL17775416	0.89	EP300 (0.48)	MAPTGAAMAPK1NPC1RAB9A
	SCHEMBL16392500	0.89	EP300 (0.52)	MAPTGAAMAPK1NPC1RAB9A
	SCHEMBL17784953	0.87	EP300 (0.56)	MAPTGAAMAPK1RAB9AEP300
	SCHEMBL19601406	0.87	EP300 (0.46)	MAPTGAAMAPK1NPC1RAB9A
	SCHEMBL21137817	0.84	GAA (0.42)	MAPTGAAMAPK1RAB9AEP300
	SCHEMBL17779609	0.84	MAPT (0.41)	MAPTMAPK1NPC1RAB9AEP300
	SCHEMBL19608099	0.83	EP300 (0.43)	MAPTGAAMAPK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.