Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 5/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16371049 | 0.89 | MAPT (0.48) | EP300MAPTGAAMAPK1NPC1 | |
| SCHEMBL16392500 | 0.86 | EP300 (0.52) | EP300MAPTGAAMAPK1NPC1 | |
| SCHEMBL28514797 | 0.81 | EP300 (0.37) | EP300MAPTNPC1RAB9ABCL2 | |
| SCHEMBL16392463 | 0.81 | EP300 (0.57) | EP300GAARAB9ATOP2ABCL2 | |
| SCHEMBL17775442 | 0.81 | ALDH1A1 (0.47) | EP300MAPTGAAMAPK1NPC1 | |
| SCHEMBL17784953 | 0.79 | EP300 (0.56) | EP300MAPTGAAMAPK1RAB9A | |
| SCHEMBL16392496 | 0.79 | AR (0.58) | EP300MAPTGAAARPELP1 | |
| SCHEMBL17775416 | 0.79 | EP300 (0.48) | EP300MAPTGAAMAPK1NPC1 | |
| SCHEMBL19601406 | 0.79 | EP300 (0.46) | EP300MAPTGAAMAPK1NPC1 | |
| SCHEMBL19608100 | 0.78 | EP300 (0.49) | EP300MAPTMAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793424-B | Ascomycetes amides | 亥姆霍兹感染研究中心有限公司 | 2021-02-19 | — | — | CN | disclosed |