Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28521004 | 1.00 | TLR8 (0.53) | TLR8KDM4EUSP2ALDH1A1GLA | |
| SCHEMBL23044015 | 0.98 | TLR8 (0.52) | TLR8KDM4EUSP2ALDH1A1GLA | |
| SCHEMBL28014894 | 0.94 | NCF1 (0.53) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL8907350 | 0.92 | ACHE (0.56) | TLR8KDM4EUSP2ALDH1A1GLA | |
| SCHEMBL8908598 | 0.92 | ACHE (0.56) | TLR8KDM4EUSP2ALDH1A1GLA | |
| SCHEMBL8907361 | 0.92 | ACHE (0.56) | TLR8KDM4EUSP2ALDH1A1GLA | |
| SCHEMBL8908674 | 0.92 | ACHE (0.56) | TLR8KDM4EUSP2ALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL10611760 | 0.91 | ACHE (0.54) | TLR8KDM4EUSP2ALDH1A1GLA | |
| Water SCHEMBL5569079 | 0.91 | ACHE (0.54) | TLR8KDM4EUSP2ALDH1A1GLA | |
| SCHEMBL8912375 | 0.91 | ACHE (0.58) | TLR8KDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250142-B | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2021-01-26 | — | — | CN | disclosed |