Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 4/20 | 0.37 |
| ▸ | WEE1 | P30291 | 2/20 | 0.37 |
| ▸ | EPHB3 | P54753 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14462703 | 0.87 | NPC1 (0.51) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL1931323 | 0.85 | RAB9A (0.49) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL5330792 | 0.78 | KDM4E (0.54) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL672683 | 0.77 | PPARG (0.46) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL294530 | 0.76 | NPC1 (0.56) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL29481329 | 0.76 | NPC1 (0.56) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL9813570 | 0.76 | NPC1 (0.51) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL1921992 | 0.76 | NPC1 (0.41) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL1921750 | 0.76 | NPC1 (0.41) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL14462716 | 0.76 | NPC1 (0.50) | NPC1RAB9ALMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461898-B | Dual cure process using thermally latent tin catalysts | 科思创德国股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-109071748-B | Process for making polyisocyanurate composites | 科思创德国股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-109071762-B | Polyisocyanurate plastic containing siloxane group and method for producing same | 科思创德国股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-110023348-B | Method for producing an object from a precursor and use of a radically crosslinkable resin in an additive manufacturing process | 科思创德国股份有限公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-113614138-A | Two-component polyurethane coatings having improved pot life without loss of weatherability | 科思创知识产权两合公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-113165259-A | Film region functionalized by means of 3D printing for modifying the surface of a workpiece | 科思创知识产权两合公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113165269-A | Method of producing an article for additive manufacturing and treatment | 科思创知识产权两合公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-107922574-B | Scratch-resistant water-based 2K PU coating | 科思创德国股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-107531876-B | Polyisocyanurate plastics having high thermal stability | 科思创德国股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-107438635-B | Process for making polyisocyanurate plastics | 科思创德国股份有限公司 | 2021-01-19 | — | — | CN | disclosed |