SCHEMBL672683

SCHEMBL672683

Cc1ccc(O)c(-n2nc3ccccc3n2)c1C(C(=O)O)(C(=O)O)c1c(C)ccc(O)c1-n1nc2ccccc2n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46
NPC1 O15118 6/20 0.42
RAB9A P51151 6/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 4/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 3/20 0.34
ALDH1A1 P00352 3/20 0.34
PKMYT1 Q99640 4/20 0.34
WEE1 P30291 2/20 0.34
EPHB3 P54753 2/20 0.34
POLB P06746 2/20 0.33
PARP1 P09874 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
KMT2A Q03164 1/20 0.33
CASP3 P42574 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28515215 0.77 NPC1 (0.53) PPARGPPARANPC1RAB9ALMNA
SCHEMBL14462703 0.76 NPC1 (0.51) PPARGPPARANPC1RAB9ALMNA
SCHEMBL1931323 0.71 RAB9A (0.49) PPARGPPARANPC1RAB9ALMNA
SCHEMBL6914110 0.70 PPARG (0.41) PPARGPPARANPC1RAB9ALMNA
SCHEMBL135250 0.70 HDAC6 (0.38) PPARGPPARANPC1RAB9ALMNA
SCHEMBL29973875 0.69 NPC1 (0.39) PPARGPPARANPC1RAB9ALMNA
SCHEMBL5846684 0.69 NPC1 (0.44) PPARGPPARANPC1RAB9ALMNA
SCHEMBL29201450 0.68 PPARG (0.40) PPARGPPARANPC1RAB9ALMNA
SCHEMBL17212261 0.68 NPC1 (0.43) PPARGPPARANPC1RAB9ALMNA
SCHEMBL5330792 0.68 KDM4E (0.54) NPC1RAB9ALMNAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4520793-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION Mitsubishi Chemical Corporation (JP) 2025-03-12 EP disclosed
US-20250051564-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION MITSUBISHI CHEMICAL CORPORATION (JP) 2025-02-13 US disclosed
WO-2024038853-A1 RESIN COMPOSITION, PELLETS, AND MOLDED ARTICLE 三菱ケミカル株式会社 2024-02-22 WO disclosed
US-7968632-B2 Polycarbonate resin composition and process for producing thereof MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2011-06-28 US disclosed
EP-1892266-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES MITSUBISHI ENG PLASTICS CORP (JP) 2010-07-21 EP disclosed
US-20090186967-A1 Polycarbonate resin composition and process for producing thereof MITSUBISHI ENGINEERING PLASTICS CORPORATION (JP) 2009-07-23 US disclosed
EP-1892266-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES Mitsubishi Engineering-Plastics Corporation (JP) 2008-02-27 EP disclosed
US-6762250-B2 TRANSPARENCY, FLUIDITY; CONTAINING POLYSILOXANE HAVING AT LEAST AROMATIC HYDROCARBON FUNCTIONALITY, CARBOXYLIC ACID ESTER AND/OR ETHER LINKAGES AND PHOSPHORIC ESTER GROUP ATTACHMENT MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-07-13 US disclosed
US-20040054116-A1 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION 2004-03-18 US disclosed