Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 10/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28515245 | 1.00 | DHFR (0.58) | DHFRTSHRADORA1TLR8GPBAR1 | |
| SCHEMBL28503565 | 0.87 | LMNA (0.52) | DHFRTLR8 | |
| SCHEMBL28514142 | 0.87 | LMNA (0.52) | DHFRTLR8 | |
| SCHEMBL28905581 | 0.82 | DHFR (0.56) | DHFRTSHRTLR8GPBAR1 | |
| SCHEMBL28905528 | 0.82 | DHFR (0.56) | DHFRTSHRTLR8GPBAR1 | |
| SCHEMBL28514968 | 0.81 | ADORA1 (0.50) | DHFRADORA1 | |
| SCHEMBL28906706 | 0.75 | TLR8 (0.54) | TLR8 | |
| SCHEMBL28503550 | 0.75 | TLR8 (0.54) | TLR8 | |
| SCHEMBL28072416 | 0.75 | APP (0.48) | ADORA1TLR8 | |
| SCHEMBL28504818 | 0.75 | TLR8 (0.51) | TSHRTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250142-B | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2021-01-26 | — | — | CN | disclosed |