SCHEMBL2851533

SCHEMBL2851533

CCCCCCC1CCCCC(CC(C(=O)O)C(=O)O)C1CC(C(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
TP53 P04637 1/20 0.37
NAAA Q02083 3/20 0.36
GPR84 Q9NQS5 3/20 0.35
FFAR1 O14842 1/20 0.35
MAPT P10636 1/20 0.34
LCK P06239 1/20 0.34
PPARD Q03181 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
EPHX1 P07099 4/20 0.34
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2859878 0.97 ALOX5 (0.44) ALOX5TP53NAAAGPR84FFAR1
SCHEMBL2857009 0.94 ALOX5 (0.46) ALOX5TP53GPR84FFAR1MAPT
SCHEMBL2858214 0.91 ALOX5 (0.46) ALOX5TP53NAAAGPR84FFAR1
SCHEMBL2854070 0.87 ALOX5 (0.49) ALOX5TP53GPR84FFAR1MAPT
SCHEMBL2862180 0.87 ALOX5 (0.49) ALOX5TP53GPR84FFAR1MAPT
SCHEMBL2859995 0.81 ALOX5 (0.57) ALOX5TP53GPR84FFAR1MAPT
SCHEMBL2853609 0.79 ALOX5 (0.44) ALOX5TP53GPR84FFAR1MAPT
SCHEMBL2853194 0.76 ALOX5 (0.47) ALOX5TP53GPR84FFAR1MAPT
SCHEMBL2855911 0.74 EPHX1 (0.34) EPHX1
SCHEMBL2861061 0.72 GRIN2D (0.33) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822366-B2 Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin MITSUI CHEMICALS, INC. (JP) 2014-09-02 US disclosed
EP-2206731-B1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2013-08-28 EP disclosed
US-20100227991-A1 SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN MITSUI CHEMICALS, INC. (JP) 2010-09-09 US disclosed
EP-2206731-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-07-14 EP disclosed