SCHEMBL2859995

SCHEMBL2859995

CCCCCCC1CC(CCCCCC)C(CC(C(=O)O)C(=O)O)C1CC(C(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.57
TBXA2R P21731 1/20 0.40
PTGFR P43088 1/20 0.40
PTGER2 P43116 1/20 0.40
GPR84 Q9NQS5 3/20 0.39
FFAR1 O14842 1/20 0.39
ALDH1A1 P00352 2/20 0.39
EPHX2 P34913 1/20 0.38
MAPT P10636 1/20 0.38
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
TP53 P04637 1/20 0.38
TRPV1 Q8NER1 3/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2862180 0.90 ALOX5 (0.49) ALOX5TBXA2RPTGFRPTGER2GPR84
SCHEMBL2854070 0.90 ALOX5 (0.49) ALOX5TBXA2RPTGFRPTGER2GPR84
SCHEMBL2858214 0.87 ALOX5 (0.46) ALOX5TBXA2RPTGFRPTGER2GPR84
SCHEMBL2857009 0.83 ALOX5 (0.46) ALOX5TBXA2RPTGFRPTGER2GPR84
SCHEMBL2859878 0.81 ALOX5 (0.44) ALOX5TBXA2RPTGFRPTGER2GPR84
SCHEMBL2851533 0.81 ALOX5 (0.44) ALOX5GPR84FFAR1EPHX2MAPT
SCHEMBL29768555 0.76 ALOX5 (0.62) ALOX5TBXA2RPTGFRPTGER2GPR84
SCHEMBL2855861 0.76 CA1 (0.32) ALOX5
SCHEMBL2853194 0.75 ALOX5 (0.47) ALOX5TBXA2RPTGFRPTGER2GPR84
SCHEMBL1925051 0.74 ALOX5 (0.65) ALOX5GPR84FFAR1ALDH1A1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822366-B2 Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin MITSUI CHEMICALS, INC. (JP) 2014-09-02 US disclosed
EP-2206731-B1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2013-08-28 EP disclosed
US-20100227991-A1 SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN MITSUI CHEMICALS, INC. (JP) 2010-09-09 US disclosed
EP-2206731-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-07-14 EP disclosed