Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528298 | 0.86 | XDH (0.57) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL28526217 | 0.84 | XDH (0.53) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL28524511 | 0.80 | XDH (0.56) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL28519542 | 0.80 | XDH (0.57) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL28524510 | 0.80 | XDH (0.56) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL28525707 | 0.78 | XDH (0.59) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL28518705 | 0.76 | MAPT (0.58) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL28528301 | 0.76 | MAPT (0.58) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL28519314 | 0.73 | XDH (0.55) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL1730801 | 0.71 | MAPT (0.63) | NPC1RAB9AMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759532-B | Benzoxazole-2-ethyl oxime derivative, and preparation method and application thereof | 苏州大学 | 2021-02-12 | — | — | CN | disclosed |