Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28518705 | 1.00 | MAPT (0.58) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL29953526 | 0.77 | MAPT (0.63) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL7315076 | 0.77 | NPC1 (0.63) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL1730801 | 0.77 | MAPT (0.63) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL28515348 | 0.76 | NPC1 (0.45) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL28882874 | 0.76 | NPC1 (0.61) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| Benzene SCHEMBL6030702 | 0.76 | MAPT (0.61) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL28526217 | 0.75 | XDH (0.53) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL9848762 | 0.74 | NPC1 (0.70) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL2125047 | 0.74 | NPC1 (0.70) | MAPTNPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759532-B | Benzoxazole-2-ethyl oxime derivative, and preparation method and application thereof | 苏州大学 | 2021-02-12 | — | — | CN | disclosed |