Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520271 | 0.91 | POLB (0.58) | IKBKBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28511901 | 0.86 | DNM1 (0.58) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL28506872 | 0.82 | GAA (0.70) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17988197 | 0.81 | IKBKB (0.69) | IKBKBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28517632 | 0.81 | MAPT (0.62) | IKBKBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15317962 | 0.80 | MAPT (0.69) | IKBKBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28506875 | 0.80 | MAPT (0.69) | IKBKBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL31005085 | 0.78 | IKBKB (0.73) | IKBKBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28511869 | 0.78 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28519771 | 0.78 | CA12 (0.58) | IKBKBMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079744-B | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | disclosed |