Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.71 |
| ▸ | KIT | P10721 | 5/20 | 0.71 |
| ▸ | ULK1 | O75385 | 14/20 | 0.67 |
| ▸ | ULK2 | Q8IYT8 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17545176 | 0.86 | ULK1 (0.88) | FLT3KITULK1ULK2 | |
| SCHEMBL5806495 | 0.83 | ULK1 (0.76) | FLT3KITULK1ULK2 | |
| SCHEMBL28515711 | 0.83 | FLT3 (1.00) | FLT3KITULK1ULK2 | |
| SCHEMBL28507195 | 0.83 | FLT3 (0.83) | FLT3KITULK1ULK2 | |
| SCHEMBL1916412 | 0.82 | FLT3 (0.67) | FLT3KITULK1ULK2 | |
| SCHEMBL1916411 | 0.82 | FLT3 (0.67) | FLT3KITULK1ULK2 | |
| SCHEMBL1917078 | 0.82 | FLT3 (0.67) | FLT3KITULK1ULK2 | |
| SCHEMBL17544373 | 0.80 | ULK1 (1.00) | FLT3KITULK1ULK2 | |
| SCHEMBL1916420 | 0.80 | FLT3 (0.65) | FLT3KITULK1ULK2 | |
| SCHEMBL1916421 | 0.80 | FLT3 (0.65) | FLT3KITULK1ULK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732548-A | N2-carbamyl aromatic ring-2-aminopyrimidine derivatives and medical application thereof | UNIV ZHEJIANG | 2020-10-02 | — | — | CN | claimed |
| CN-111732548-B | N2-carbamyl aromatic ring-2-aminopyrimidine derivatives and medical application thereof | 浙江大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-111732548-A | N2-carbamyl aromatic ring-2-aminopyrimidine derivatives and medical application thereof | UNIV ZHEJIANG | 2020-10-02 | — | — | CN | disclosed |