Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 15/20 | 0.76 |
| ▸ | FLT3 | P36888 | 3/20 | 0.65 |
| ▸ | KIT | P10721 | 2/20 | 0.65 |
| ▸ | GSK3A | P49840 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.62 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.60 |
| ▸ | ULK2 | Q8IYT8 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17547453 | 0.93 | ULK1 (0.88) | ULK1ULK2 | |
| SCHEMBL17547443 | 0.87 | ULK1 (1.00) | ULK1ULK2 | |
| SCHEMBL28906657 | 0.84 | FLT3 (0.57) | ULK1FLT3KITGSK3AGSK3B | |
| SCHEMBL28906656 | 0.84 | FLT3 (0.57) | ULK1FLT3KITGSK3AGSK3B | |
| SCHEMBL28515708 | 0.83 | FLT3 (0.71) | ULK1FLT3KITULK2 | |
| SCHEMBL21258189 | 0.82 | ULK1 (0.71) | ULK1FLT3KITULK2 | |
| SCHEMBL1916412 | 0.81 | FLT3 (0.67) | ULK1FLT3KITULK2 | |
| SCHEMBL1916411 | 0.81 | FLT3 (0.67) | ULK1FLT3KITULK2 | |
| SCHEMBL1917489 | 0.81 | ULK1 (0.70) | ULK1FLT3KITMAPK3ULK2 | |
| SCHEMBL1917484 | 0.81 | ULK1 (0.70) | ULK1FLT3KITMAPK3ULK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006091737-A1 | MODULATORS OF GSK-3 ACTIVITY | KEMIA, INC. (US) | 2006-08-31 | — | — | WO | claimed |