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Phenylalanine Amide

Phenylalanine Amide

SCHEMBL28515941

CC(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCCN)C(=O)N1CCC[C@H]1C(=O)NC(C(=O)NC(C(=O)NC(CCC(N)=O)C(=O)O)C(C)O)C(C)C.NC(=O)C(N)Cc1ccccc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 1/20 0.59
▸ IL23R Q5VWK5 1/20 0.58
▸ OPRD1 P41143 4/20 0.56
▸ OPRM1 P35372 1/20 0.56
▸ OPRK1 P41145 1/20 0.56
▸ F2 P00734 1/20 0.55
▸ CALCRL Q16602 1/20 0.55
▸ NTSR2 O95665 2/20 0.54
▸ NTSR1 P30989 2/20 0.54
▸ SORT1 Q99523 2/20 0.54
▸ NMUR2 Q9GZQ4 1/20 0.53
▸ NMUR1 Q9HB89 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28515939 0.88 IL23R (0.55) SLC6A2IL23ROPRD1OPRM1OPRK1
SCHEMBL29530950 0.87 SLC6A2 (0.70) SLC6A2OPRD1OPRM1OPRK1CALCRL
SCHEMBL29530789 0.87 SLC6A2 (0.70) SLC6A2OPRD1OPRM1OPRK1CALCRL
SCHEMBL31151473 0.86 OPRD1 (0.61) SLC6A2OPRD1OPRM1OPRK1F2
SCHEMBL29591831 0.85 SLC6A2 (0.62) SLC6A2OPRD1OPRM1OPRK1F2
SCHEMBL30242503 0.85 SLC6A2 (0.63) SLC6A2OPRD1OPRM1OPRK1NTSR2
SCHEMBL31362624 0.84 SLC6A2 (0.59) SLC6A2OPRD1OPRM1OPRK1F2
SCHEMBL30350851 0.84 SLC6A2 (0.57) SLC6A2OPRM1F2NTSR2NTSR1
SCHEMBL31410882 0.84 SLC6A2 (0.67) SLC6A2OPRD1OPRM1OPRK1NTSR2
SCHEMBL29655338 0.84 NTSR2 (0.62) SLC6A2OPRM1F2NTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107188937-B Preparation method of drug RIP1183 for resisting multi-drug resistant staphylococcus infection 中国人民解放军第四军医大学 2021-02-09 — — CN claimed
CN-107188937-B Preparation method of drug RIP1183 for resisting multi-drug resistant staphylococcus infection 中国人民解放军第四军医大学 2021-02-09 — — CN disclosed
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