Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR2 | O95665 | 10/20 | 0.62 |
| ▸ | NTSR1 | P30989 | 10/20 | 0.62 |
| ▸ | SORT1 | Q99523 | 8/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29465927 | 0.90 | SLC6A2 (0.62) | NTSR2NTSR1SORT1SLC6A2 | |
| SCHEMBL29694378 | 0.89 | NTSR1 (0.64) | NTSR2NTSR1SORT1OPRM1 | |
| SCHEMBL30844342 | 0.89 | NTSR2 (0.57) | NTSR2NTSR1SORT1SLC6A2F2 | |
| SCHEMBL30844350 | 0.89 | KDM1A (0.62) | — | |
| SCHEMBL30560038 | 0.88 | NTSR2 (0.65) | NTSR2NTSR1SORT1F2OPRM1 | |
| SCHEMBL29894426 | 0.88 | NTSR1 (0.63) | NTSR2NTSR1SORT1F2OPRM1 | |
| SCHEMBL30923399 | 0.87 | SLC6A2 (0.58) | NTSR2NTSR1SORT1SLC6A2F2 | |
| SCHEMBL31362630 | 0.87 | OPRM1 (0.65) | SLC6A2F2OPRM1 | |
| SCHEMBL30350851 | 0.87 | SLC6A2 (0.57) | NTSR2NTSR1SORT1SLC6A2F2 | |
| SCHEMBL29591831 | 0.87 | SLC6A2 (0.62) | SLC6A2F2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | NTSR2 772/4885NTSR1 810/4885SORT1 2293/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | NTSR2 772/4885NTSR1 810/4885SORT1 2293/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | NTSR2 772/4885NTSR1 810/4885SORT1 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.