Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855140 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1HSD11B1MAPT | |
| SCHEMBL2843430 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRL3MBTL1HSD11B1MAPT | |
| SCHEMBL2846340 | 0.81 | TYK2 (0.42) | ALDH1A1TSHRL3MBTL1HSD11B1MAPT | |
| SCHEMBL2846682 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1HSD11B1MAPT | |
| SCHEMBL2851117 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TSHRL3MBTL1HSD11B1MAPT | |
| SCHEMBL2008495 | 0.76 | ALDH1A1 (0.60) | ALDH1A1TSHRL3MBTL1HSD11B1MAPT | |
| SCHEMBL13354146 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRL3MBTL1HSD11B1MAPT | |
| SCHEMBL2875512 | 0.74 | ABCB1 (0.42) | ALDH1A1TSHRL3MBTL1HSD11B1MAPT | |
| SCHEMBL13354145 | 0.73 | TYK2 (0.41) | ALDH1A1TSHRL3MBTL1HSD11B1MAPT | |
| SCHEMBL13354144 | 0.72 | MAPK13 (0.49) | ALDH1A1TSHRL3MBTL1HSD11B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130509-A1 | NOVEL ANTIBIOTICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWE- TENSCHAPPELIJK ONDERZOEK TNO (NL) | 2010-05-27 | — | — | US | disclosed |
| EP-2139872-A1 | NOVEL ANTIBIOTICS | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008120992-A1 | NOVEL ANTIBIOTICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130509-A1 | NOVEL ANTIBIOTICS | TMEM165, LAS1L, RPS2 | ALDH1A1 4431/4885TSHR 3686/4885L3MBTL1 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.