Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 19/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30183010 | 0.82 | TGFBR1 (0.65) | TGFBR1MAPK14CYP1A2 | |
| SCHEMBL4487787 | 0.82 | TGFBR1 (0.47) | TGFBR1MAPK14 | |
| SCHEMBL28510134 | 0.81 | TGFBR1 (0.63) | TGFBR1MAPK14CYP1A2 | |
| SCHEMBL28510984 | 0.80 | TGFBR1 (0.59) | TGFBR1MAPK14CYP1A2 | |
| SCHEMBL38661638 | 0.77 | TGFBR1 (0.46) | TGFBR1MAPK14 | |
| SCHEMBL22228617 | 0.77 | TGFBR1 (0.40) | TGFBR1MAPK14CYP1A2 | |
| SCHEMBL13680555 | 0.76 | TGFBR1 (0.55) | TGFBR1MAPK14 | |
| SCHEMBL6764903 | 0.76 | TGFBR1 (0.66) | TGFBR1MAPK14 | |
| SCHEMBL30182848 | 0.76 | TGFBR1 (0.63) | TGFBR1MAPK14CYP1A2 | |
| SCHEMBL22228605 | 0.75 | TGFBR1 (0.47) | TGFBR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112266378-A | Imidazole derivative containing indazole structure and preparation method and application thereof | 延边大学 | 2021-01-26 | — | — | CN | claimed |
| CN-112266378-B | Imidazole derivative containing indazole structure and preparation method and application thereof | 延边大学 | 2021-10-12 | — | — | CN | disclosed |
| CN-112266378-A | Imidazole derivative containing indazole structure and preparation method and application thereof | 延边大学 | 2021-01-26 | — | — | CN | disclosed |