Trifluoromethylbenzene

Trifluoromethylbenzene

SCHEMBL28516552

FC(F)(F)c1ccccc1.FC(F)(F)c1ccccc1.N=C=N

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.78
ALDH1A1 P00352 1/20 0.78
KIF11 P52732 2/20 0.56
TRPV6 Q9H1D0 1/20 0.46
CYP19A1 P11511 1/20 0.44
BACE1 P56817 1/20 0.42
PTPN1 P18031 1/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
OPRM1 P35372 1/20 0.39
OPRL1 P41146 1/20 0.39
ACP3 P15309 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
KCNN4 O15554 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethylbenzene SCHEMBL2906474 0.90 TSHR (0.70) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL6154213 0.90 TSHR (0.70) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL8692 0.88 TSHR (1.00) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL27760126 0.88 TSHR (1.00) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL175647 0.88 TSHR (1.00) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL9482280 0.85 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL14121438 0.85 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL7870246 0.85 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL1830622 0.85 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL22806921 0.85 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110212188-B Metal iron oxide growing by taking carbon as framework support and preparation method and application thereof 陕西科技大学 2021-02-09 CN claimed
CN-110212188-B Metal iron oxide growing by taking carbon as framework support and preparation method and application thereof 陕西科技大学 2021-02-09 CN disclosed
CN-110212188-B Metal iron oxide growing by taking carbon as framework support and preparation method and application thereof 陕西科技大学 2021-02-09 CN disclosed