SCHEMBL28516595

SCHEMBL28516595

C=C(C(=O)O)C(=O)OCC(C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
MAPT P10636 1/20 0.44
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KMT2A Q03164 2/20 0.40
TAAR1 Q96RJ0 2/20 0.39
TRPA1 O75762 3/20 0.39
LTB4R Q15722 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38
HPGD P15428 2/20 0.38
TSHR P16473 2/20 0.38
MEN1 O00255 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28516593 0.93 ALDH1A1 (0.46) ALDH1A1MAPTCYP1A2CYP2D6PKM
SCHEMBL17550615 0.88 ALDH1A1 (0.56) ALDH1A1MAPTSMN1; SMN2KMT2AHPGD
SCHEMBL17550625 0.88 KMT2A (0.49) ALDH1A1MAPTCYP1A2CYP2D6PKM
SCHEMBL296808 0.85 TSHR (0.55) ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL14468427 0.81 CYP1A2 (0.43) ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL28352044 0.81 CYP1A2 (0.49) ALDH1A1MAPTCYP1A2CYP2D6PKM
SCHEMBL11142924 0.80 CYP1A2 (0.42) ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL1838251 0.79 CYP1A2 (0.47) ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL1838254 0.79 CYP1A2 (0.47) ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL28452045 0.79 CYP1A2 (0.46) ALDH1A1MAPTCYP1A2CYP2D6PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112969756-A Acrylic resin composition, crosslinked material, and method for producing crosslinked material 株式会社日本触媒 2021-06-15 CN disclosed
CN-107075037-B Polymer comprising one or more 1, 1-disubstituted alkene compounds and polymer compositions thereof 赛鲁斯股份有限公司 2021-02-09 CN disclosed