Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL28196913 | 0.93 | TSHR (0.47) | TSHRHPGDALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL713937 | 0.91 | TSHR (0.60) | TSHRALDH1A1KMT2AFFAR1ELANE | |
| SCHEMBL721729 | 0.89 | TSHR (0.53) | TSHRHPGDALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL28516593 | 0.88 | ALDH1A1 (0.46) | TSHRHPGDALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL14468427 | 0.86 | CYP1A2 (0.43) | TSHRHPGDALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL714605 | 0.86 | TSHR (0.58) | TSHRALDH1A1KMT2AELANEPOLB | |
| SCHEMBL3180135 | 0.86 | TSHR (0.53) | TSHRHPGDALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL28516595 | 0.85 | ALDH1A1 (0.44) | TSHRHPGDALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL16232460 | 0.84 | TSHR (0.51) | TSHRALDH1A1NPSR1KMT2AFFAR1 | |
| SCHEMBL1685754 | 0.83 | TSHR (0.50) | TSHRHPGDALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279959-A | Ophthalmic polymer material, method for the production and use thereof | 康小林 | 2021-01-29 | — | — | CN | claimed |
| EP-2225325-A2 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | Alcon, Inc. (CH) | 2010-09-08 | — | — | EP | claimed |
| WO-2009015256-A2 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON, INC. (CH) | 2009-01-29 | — | — | WO | claimed |
| US-RE38935-E1 | Intraocular lenses made from polymeric compositions and monomers useful in said compositions | ADVANCED MEDICAL OPTICS, INC. (US) | 2006-01-10 | — | — | US | claimed |
| US-6645246-B1 | Intraocular lens with surrounded lens zone | ADVANCED MEDICAL OPTICS, INC. | 2003-11-11 | — | — | US | claimed |
| EP-1177227-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2002-02-06 | — | — | EP | claimed |
| US-6245106-B1 | DEFORMABLE INTRAOCULAR LENSES HAVING REDUCED SURFACE TACKINESS MADE FROM 2-PHENYLPROPYL ACRYLATE/METHACRYLATE BASED COMPOSITIONS, FOR INSERTION INTO A MAMMALIAN EYE FOR VISION CORRECTION | ALLERGAN SALES, INC. | 2001-06-12 | — | — | US | claimed |
| WO-2000061646-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2000-10-19 | — | — | WO | claimed |
| WO-2000060383-A1 | INTRAOCULAR LENSES MADE FROM POLYMERIC COMPOSITIONS AND MONOMERS USEFUL IN SAID COMPOSITIONS | ALLERGAN SALES, INC. (US) | 2000-10-12 | — | — | WO | claimed |
| US-5110709-A | Photoresists of excellent image resolution | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-05 | — | — | US | claimed |
| US-12611296-B2 | Intraocular lens materials and components | ALCON INC. (CH) | 2026-04-28 | — | — | US | disclosed |
| EP-4267708-B1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | INFINEUM INT LTD (GB) | 2025-07-02 | — | — | EP | disclosed |
| WO-2025093198-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC DEVICES | BAUSCH + LOMB IRELAND LIMITED (IE) | 2025-05-08 | — | — | WO | disclosed |
| US-12281203-B2 | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2025-04-22 | — | — | US | disclosed |
| US-20240350256-A1 | INTRAOCULAR LENS MATERIALS AND COMPONENTS | ALCON INC. (CH) | 2024-10-24 | — | — | US | disclosed |
| US-5648190-A | Method of forming color images and apparatus used therefor | FUJI PHOTO FILM CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| US-5582943-A | TRANSFER LAYER HAVING A SHELL-CORE POLYMER OF THERMOPLASTIC RESINS OF DIFFERING GLASS TRANSITION TEMPERATURES AND SOFTENING POINTS; ACCURACY; QUALITY; RELEASABILITY; ADHESION; RETOUCHING, SEALING AND STORING STABILITY | FUJI PHOTO FILM CO., LTD (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5582941-A | FORMING COLOR IMAGE ON ELECTROGRAPHIC PHOTORECEPTOR, FORMING RELEASABLE TRANSFER LAYER HAVING IMAGE THEREON, TRANSFERRING IMAGE ONTO RECEPTOR THEN ONTO RECEIVER MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5576143-A | SEMICONDUCTORS, PHOTORESISTS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| US-5110709-A | Photoresists of excellent image resolution | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12611296-B2 | Intraocular lens materials and components | CRYAA, AQP4, CRYZ | TSHR 1038/4885HPGD 1164/4885ALDH1A1 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.