Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | PLEC | Q15149 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707306 | 0.93 | ALDH1A1 (0.41) | THRBTSHRALDH1A1MAPTCA12 | |
| SCHEMBL21450838 | 0.91 | THRB (0.47) | THRBTSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14934926 | 0.89 | THRB (0.44) | THRBTSHRALDH1A1MAPTKDM4E | |
| SCHEMBL10807918 | 0.87 | THRB (0.38) | THRBTSHRALDH1A1MAPTKDM4E | |
| SCHEMBL27859554 | 0.84 | TSHR (0.48) | THRBTSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27357 | 0.83 | THRB (0.63) | THRBTSHRALDH1A1MAPTKDM4E | |
| Hydroxyl Radical SCHEMBL28295756 | 0.81 | THRB (0.61) | THRBTSHRALDH1A1MAPTKDM4E | |
| SCHEMBL31377967 | 0.81 | THRB (0.41) | THRBTSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19679991 | 0.80 | THRB (0.54) | THRBTSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4619144 | 0.79 | THRB (0.44) | THRBTSHRALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107075037-B | Polymer comprising one or more 1, 1-disubstituted alkene compounds and polymer compositions thereof | 赛鲁斯股份有限公司 | 2021-02-09 | — | — | CN | disclosed |