Adamantane

Adamantane

SCHEMBL28516622

C1C2CC3CC1CC(C2)C3.O=C(O)c1cccc2c1CCCCC2

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 5/20 0.49
BCL2L1 Q07817 1/20 0.46
BAD Q92934 1/20 0.46
GFER P55789 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
RXRA P19793 5/20 0.43
RXRB P28702 4/20 0.43
RXRG P48443 4/20 0.43
FABP4 P15090 2/20 0.41
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5755502 0.91 CXCR5 (0.55) CXCR5BCL2L1BADGFERMEN1
SCHEMBL29493191 0.89 CXCR5 (0.56) CXCR5BCL2L1BADGFERMEN1
SCHEMBL783869 0.89 CXCR5 (0.56) CXCR5BCL2L1BADGFERMEN1
Hydrochloric Acid SCHEMBL2398251 0.88 CXCR5 (0.55) CXCR5BCL2L1BADGFERMEN1
SCHEMBL3613341 0.86 CXCR5 (0.53) CXCR5BCL2L1BADGFERMEN1
SCHEMBL10468902 0.81 BCL2L1 (0.50) CXCR5BCL2L1BADGFERMEN1
SCHEMBL1159789 0.79 BCL2L1 (0.52) CXCR5BCL2L1BADGFERMEN1
SCHEMBL11814300 0.78 BCL2L1 (0.55) CXCR5BCL2L1BADGFERMEN1
SCHEMBL11001708 0.78 HSP90AA1 (0.51) CXCR5BCL2L1BADGFERMEN1
SCHEMBL29950657 0.78 ALDH1A1 (0.50) CXCR5GFERALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110204468-B Asymmetric synthesis method of chiral alpha-thiocyano cyclic ketonic acid ester compound 浙江工业大学 2021-02-02 CN disclosed