SCHEMBL29950657

SCHEMBL29950657

O=C(O)c1cccc2c1CC2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
ALOX15 P16050 1/20 0.50
TRPA1 O75762 1/20 0.47
HSP90AA1 P07900 2/20 0.45
CXCR5 P32302 1/20 0.44
TSHR P16473 1/20 0.43
NR4A1 P22736 1/20 0.43
NR4A2 P43354 1/20 0.43
NR4A3 Q92570 1/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HMGB1 P09429 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15330692 1.00 ALDH1A1 (0.50) ALDH1A1ALOX15TRPA1HSP90AA1CXCR5
SCHEMBL3613341 0.87 CXCR5 (0.53) ALDH1A1ALOX15TRPA1CXCR5KDM4E
SCHEMBL29493191 0.87 CXCR5 (0.56) ALDH1A1ALOX15TRPA1CXCR5GFER
SCHEMBL783869 0.87 CXCR5 (0.56) ALDH1A1ALOX15TRPA1CXCR5GFER
SCHEMBL5755502 0.85 CXCR5 (0.55) ALDH1A1ALOX15CXCR5GFER
Hydrochloric Acid SCHEMBL2398251 0.85 CXCR5 (0.55) ALDH1A1ALOX15CXCR5GFER
SCHEMBL16990754 0.83 ALDH1A1 (0.42) ALDH1A1ALOX15TRPA1HSP90AA1CXCR5
SCHEMBL242419 0.82 AKR1C3 (0.57) ALDH1A1CXCR5NR4A1KDM4EMAPT
SCHEMBL4915504 0.82 TRPA1 (0.56) ALDH1A1ALOX15TRPA1HSP90AA1TSHR
SCHEMBL11524733 0.82 AKR1B1 (0.56) ALDH1A1ALOX15TRPA1HSP90AA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed