SCHEMBL28516652

SCHEMBL28516652

CCCC(O)COC(CC)N(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7527904 0.87 SPHK1 (0.32) LMNASMN1; SMN2
SCHEMBL12760687 0.85 GPR84 (0.41) LMNA
SCHEMBL4541455 0.77 TDP1 (0.41)
SCHEMBL28705106 0.72 LMNA (0.37) LMNASMN1; SMN2
SCHEMBL26365482 0.72 SMN1; SMN2 (0.40) LMNASMN1; SMN2
SCHEMBL16013047 0.72 SMN1; SMN2 (0.40) LMNASMN1; SMN2
SCHEMBL9650355 0.71 TSHR (0.39) LMNA
SCHEMBL28797228 0.70 TDP1 (0.42)
SCHEMBL4820365 0.68
SCHEMBL27948551 0.68 TDP1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112237628-A EBV-targeted LMP2-mRNA nano vaccine 四川大学华西医院 2021-01-19 CN claimed
CN-112237628-A EBV-targeted LMP2-mRNA nano vaccine 四川大学华西医院 2021-01-19 CN disclosed