Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 11/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516729 | 1.00 | HCRTR1 (0.33) | HCRTR1MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL28180596 | 0.69 | KDM2B (0.35) | MEN1ALDH1A1KMT2AUSP2CYP1A2 | |
| SCHEMBL28520780 | 0.69 | HPGD (0.47) | ALDH1A1KMT2ATSHR | |
| SCHEMBL28851927 | 0.64 | ALDH1A1 (0.58) | MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL31003259 | 0.61 | ALDH1A1 (0.45) | MEN1ALDH1A1KMT2A | |
| SCHEMBL24174889 | 0.60 | CHRM2 (0.36) | ALDH1A1CYP1A2HIF1ATSHR | |
| SCHEMBL15684140 | 0.60 | CHRM2 (0.36) | ALDH1A1CYP1A2HIF1ATSHR | |
| SCHEMBL17756086 | 0.60 | CHRM2 (0.36) | ALDH1A1CYP1A2HIF1ATSHR | |
| SCHEMBL26656187 | 0.60 | CHRM2 (0.36) | ALDH1A1CYP1A2HIF1ATSHR | |
| SCHEMBL26814879 | 0.60 | ALDH1A1 (0.55) | MEN1ALDH1A1KMT2ATLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107235960-B | Amide derivatives, preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2021-01-29 | — | — | CN | disclosed |