Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092578 | 0.88 | HPGD (0.49) | HPGDALDH1A1POLBSMN1; SMN2ADRB2 | |
| SCHEMBL15913974 | 0.76 | MAPT (0.42) | HPGDALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL14637849 | 0.72 | SMN1; SMN2 (0.47) | HPGDALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL28516729 | 0.69 | HCRTR1 (0.33) | ALDH1A1TSHRKMT2A | |
| SCHEMBL28516727 | 0.69 | HCRTR1 (0.33) | ALDH1A1TSHRKMT2A | |
| SCHEMBL4089859 | 0.69 | PDE2A (0.47) | ALDH1A1POLBPDE2ANPC1RAB9A | |
| SCHEMBL2436680 | 0.69 | HPGD (0.65) | HPGDALDH1A1POLBSMN1; SMN2ADRB2 | |
| SCHEMBL4085982 | 0.67 | HPGD (0.51) | HPGDALDH1A1POLBSMN1; SMN2ADRB2 | |
| SCHEMBL192942 | 0.67 | HPGD (0.77) | HPGDALDH1A1POLBSMN1; SMN2ADRB2 | |
| SCHEMBL28851927 | 0.67 | ALDH1A1 (0.58) | HPGDALDH1A1POLBSMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107235960-B | Amide derivatives, preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2021-01-29 | — | — | CN | disclosed |