SCHEMBL28516803

SCHEMBL28516803

CCC[Si](CCOCCCC1CO1)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
EPHX1 P07099 1/20 0.33
SPHK2 Q9NRA0 2/20 0.32
SPHK1 Q9NYA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7688095 0.82 SMN1; SMN2 (0.55) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL31520329 0.80 TSHR (0.39) SMN1; SMN2ALDH1A1TDP1TSHRMEN1
SCHEMBL11767225 0.79 SMN1; SMN2 (0.61) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL3627361 0.77 SMN1; SMN2 (0.67) SMN1; SMN2ALDH1A1TDP1TSHRMEN1
SCHEMBL3796286 0.77 ALDH1A1 (0.45) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL3619783 0.77 ALDH1A1 (0.56) SMN1; SMN2ALDH1A1TDP1TSHRMEN1
SCHEMBL3622192 0.76 ALDH1A1 (0.66) SMN1; SMN2ALDH1A1TDP1TSHRMEN1
SCHEMBL17255931 0.76 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1TSHREPHX1
SCHEMBL8768045 0.75 TSHR (0.56) SMN1; SMN2ALDH1A1TDP1TSHRMEN1
SCHEMBL5268562 0.74 TSHR (0.54) SMN1; SMN2ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107960095-B Coating composition and optical member 日产化学工业株式会社 2021-02-02 CN disclosed