Ethoxycarbonyl Group

Ethoxycarbonyl Group

SCHEMBL28517152

CCOC=O.Ic1cc2ccccc2o1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.44
MAOB P27338 2/20 0.40
MAOA P21397 1/20 0.40
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.38
POLB P06746 2/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
LMNA P02545 1/20 0.38
AGXT P21549 1/20 0.37
MAPK1 P28482 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP3A4 P08684 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
FLT3 P36888 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
MAPT P10636 3/20 0.36
CASP3 P42574 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxycarbonyl Group SCHEMBL28518665 0.82 CYP2A6 (0.44) CYP2A6MAOBMAOARAB9ANPC1
Ethoxycarbonyl Group SCHEMBL28526058 0.82 CYP2A6 (0.44) CYP2A6MAOBMAOARAB9ANPC1
SCHEMBL3452249 0.78 KDM4E (0.48) CYP2A6MAOBMAOARAB9ANPC1
Anthracene SCHEMBL27554619 0.76 GAA (0.41) CYP2A6RAB9ANPC1POLBALDH1A1
Naphthalene SCHEMBL27488215 0.76 ALDH1A1 (0.40) CYP2A6RAB9AALDH1A1KDM4ELMNA
Naphthalene SCHEMBL27634543 0.74 ALDH1A1 (0.39) CYP2A6ALDH1A1KDM4ELMNAMAPK1
Benzofuran SCHEMBL28100443 0.73 CYP2A6 (0.39) CYP2A6MAOBMAOAALDH1A1LMNA
SCHEMBL5541861 0.71 AGXT (0.62) CYP2A6RAB9APOLBAGXTKMT2A
Iodobenzene SCHEMBL28243369 0.71 MEN1 (0.35) CYP2A6ALDH1A1KDM4ELMNAKMT2A
Phenanthrene SCHEMBL28669665 0.70 ALDH1A1 (0.48) CYP2A6RAB9ANPC1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110092778-B Method for preparing vilazodone intermediate and vilazodone medicine by using cheap metal copper 浙江工业大学 2021-02-09 CN disclosed