SCHEMBL3452249

SCHEMBL3452249

Ic1cc2ccccc2o1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
CYP2A6 P11509 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FLT3 P36888 1/20 0.48
LOXL2 Q9Y4K0 1/20 0.48
MGLL Q99685 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TYR P14679 1/20 0.47
DAO P14920 1/20 0.47
AKR1B1 P15121 1/20 0.47
HPGD P15428 1/20 0.47
POLB P06746 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CA2 P00918 2/20 0.45
MAOB P27338 6/20 0.44
RAB9A P51151 2/20 0.44
MAOA P21397 2/20 0.44
ALDH1A1 P00352 1/20 0.44
AGXT P21549 1/20 0.44
CA12 O43570 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxycarbonyl Group SCHEMBL28517152 0.78 CYP2A6 (0.44) KDM4ECYP2A6FLT3LOXL2HSD17B10
SCHEMBL30036439 0.74 MAOB (0.63) KDM4ECYP2A6TDP1FLT3LOXL2
SCHEMBL103158 0.74 MAOB (0.63) KDM4ECYP2A6TDP1FLT3LOXL2
SCHEMBL18822720 0.73 APP (0.42) KDM4ECYP2A6FLT3HSD17B10TYR
SCHEMBL4336341 0.73 SMN1; SMN2 (0.60) KDM4EHSD17B10TYRDAOAKR1B1
SCHEMBL2150377 0.72 MAOB (0.59) KDM4ETDP1HSD17B10HPGDPOLB
SCHEMBL61411 0.71 MAOB (0.71) KDM4ETDP1FLT3HSD17B10HPGD
SCHEMBL12854020 0.71 MAOB (0.71) KDM4ETDP1FLT3HSD17B10HPGD
SCHEMBL16802955 0.70 ACHE (0.32) KDM4ECYP2A6HSD17B10RAB9AMAOA
SCHEMBL8874655 0.70 KDM4E (0.48) KDM4ECYP2A6TDP1FLT3LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111499566-A Pyridine derivative compound and preparation method thereof 南京工业大学 2020-08-07 CN claimed
CN-103108869-A Process for preparing aminobenzoylbenzofuran derivatives SANOFI SA 2013-05-15 CN claimed
WO-2024026129-A2 TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF ENSEM THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
CN-114702408-B Preparation method and application of clenbuterol impurity 南京康川济医药科技有限公司 2024-01-16 CN disclosed
EP-4234566-A1 MODIFIED NUCLEOSIDE OR NUCLEOTIDE BGI Shenzhen (CN) 2023-08-30 EP disclosed
US-20230200202-A1 ORGANIC SEMICONDUCTING COMPOUNDS Raynergy Tek Incorporation (TW) 2023-06-22 US disclosed
CN-113402559-B Cyclic organic antimony compound and preparation method thereof 湖南大学 2023-05-05 CN disclosed
EP-4115882-A1 COMPOUNDS FOR IMPROVING MRNA SPLICING The General Hospital Corporation (US) 2023-01-11 EP disclosed
CN-114702408-A Preparation method and application of Kelibaro impurity 南京康川济医药科技有限公司 2022-07-05 CN disclosed
WO-2022083686-A1 MODIFIED NUCLEOSIDE OR NUCLEOTIDE 深圳华大生命科学研究院 2022-04-28 WO disclosed
CN-113402559-A Cyclic organic antimony compound and preparation method thereof 湖南大学 2021-09-17 CN disclosed
US-4128659-A 2-NITRO-3-PHENYL-BENZOFURANS RIKER LABORATORIES, INC. (US) 1978-12-05 US disclosed
US-4124704-A ANTIMICROBIAL RIKER LABORATORIES, INC. (US) 1978-11-07 US disclosed
US-4124603-A ANTIMICROBIAL RIKER LABORATORIES, INC. (US) 1978-11-07 US disclosed
US-4124605-A ANTIMICROBIAL RIKER LABORATORIES, INC. (US) 1978-11-07 US disclosed
US-4124602-A OPTIONALLY SUBSTITUTED 3-(CYANOPHENYL)BENZOFURANS RIKER LABORATORIES, INC. (US) 1978-11-07 US disclosed
US-4067993-A Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids RIKER LABORATORIES, INC. (US) 1978-01-10 US disclosed
US-4066782-A Antimicrobial (2-nitro-3-benzofuranyl)phenylacetic acids RIKER LABORATORIES, INC. (US) 1978-01-03 US disclosed
US-4048323-A Antimicrobial (2-nitro-3-benzofuranyl)-benzoic acids RIKER LABORATORIES, INC. (US) 1977-09-13 US disclosed
US-4022908-A Use of certain 2-nitro-3-phenyl-alkoxybenzofurans in inhibiting growth of microorganisms and intermediates in the synthesis of said benzofurans RIKER LABORATORIES, INC. (US) 1977-05-10 US disclosed