SCHEMBL28517243 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	RIPK1	Q13546	2/20	0.44

▸	BCHE	P06276	1/20	0.41

▸	ACHE	P22303	1/20	0.41

▸	CALCRL	Q16602	10/20	0.40

▸	GPR119	Q8TDV5	1/20	0.39

▸	LMNA	P02545	1/20	0.39

▸	ALDH1A1	P00352	1/20	0.38

▸	TDP1	Q9NUW8	1/20	0.38

▸	PDE5A	O76074	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20835772	0.89	RIPK1 (0.44)	RIPK1BCHEACHECALCRLLMNA
SCHEMBL28528682	0.89	RIPK1 (0.47)	RIPK1CALCRLGPR119ALDH1A1PDE5A
SCHEMBL20835797	0.86	RIPK1 (0.48)	RIPK1CALCRLGPR119PDE5A
SCHEMBL28521924	0.85	RIPK1 (0.41)	RIPK1BCHEACHECALCRLGPR119
SCHEMBL21093787	0.84	CALCRL (0.42)	RIPK1CALCRL
SCHEMBL20835904	0.84	RIPK1 (0.50)	RIPK1CALCRLGPR119ALDH1A1PDE5A
SCHEMBL28521349	0.84	RIPK1 (0.50)	RIPK1CALCRLGPR119PDE5A
SCHEMBL21093662	0.84	RIPK1 (0.41)	RIPK1BCHEACHECALCRLGPR119
SCHEMBL2584143	0.84	RIPK1 (0.46)	RIPK1BCHEACHEGPR119LMNA
SCHEMBL21093793	0.83	CALCRL (0.42)	RIPK1BCHEACHECALCRL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-109476639-B	Pyrrolidine derivatives	橘生药品工业股份有限公司	2021-02-26	—	—	CN	disclosed