Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | CALCRL | Q16602 | 10/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20835797 | 0.89 | RIPK1 (0.48) | RIPK1CALCRLJAK2NTRK1PDE5A | |
| SCHEMBL28517243 | 0.89 | RIPK1 (0.44) | RIPK1CALCRLPDE5AGPR119ALDH1A1 | |
| SCHEMBL20835868 | 0.88 | RIPK1 (0.46) | RIPK1CALCRLPDE5A | |
| SCHEMBL28907112 | 0.87 | RIPK1 (0.48) | RIPK1CALCRLJAK2NTRK1PDE5A | |
| SCHEMBL20835904 | 0.87 | RIPK1 (0.50) | RIPK1CALCRLJAK2NTRK1PDE5A | |
| SCHEMBL28521349 | 0.87 | RIPK1 (0.50) | RIPK1CALCRLJAK2NTRK1PDE5A | |
| SCHEMBL28907229 | 0.84 | PKM (0.43) | RIPK1CALCRLALDH1A1 | |
| SCHEMBL28529975 | 0.84 | RIPK1 (0.47) | RIPK1CALCRLJAK2NTRK1PDE5A | |
| SCHEMBL28518941 | 0.84 | RIPK1 (0.47) | RIPK1CALCRLJAK2NTRK1PDE5A | |
| SCHEMBL28521345 | 0.84 | RIPK1 (0.47) | RIPK1CALCRLJAK2NTRK1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |