SCHEMBL28517296

SCHEMBL28517296

CC(C)(CO)COC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
EPHX1 P07099 1/20 0.32
NUDT1 P36639 1/20 0.31
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19218049 0.89 HTT (0.31) NUDT1HTT
SCHEMBL13242048 0.81 NPC1 (0.36) NPC1EPHX1NAAA
SCHEMBL27757261 0.78 NPC1 (0.38) NPC1EPHX1
SCHEMBL5642783 0.78 NPC1 (0.40) NPC1EPHX1HTTRAB9ASMN1; SMN2
Ethylene Glycol SCHEMBL27888550 0.77 NPC1 (0.32) NPC1
SCHEMBL28516406 0.76 EPHX1 (0.34) NPC1EPHX1NAAA
SCHEMBL28518300 0.76 LMNA (0.33) NPC1EPHX1NAAA
SCHEMBL28890982 0.76 NPC1 (0.34) NPC1
SCHEMBL5153335 0.76 NPC1 (0.34) NPC1EPHX1HTT
SCHEMBL18997091 0.75 NPC1 (0.37) NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106715374-B Polyether diol and process for producing the same 三菱瓦斯化学株式会社 2021-01-12 CN disclosed