SCHEMBL5153335

SCHEMBL5153335

CC(C)(O)COC1CCCC1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
HPGDS O60760 1/20 0.32
EPHX1 P07099 1/20 0.31
HTT P42858 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20064251 0.82 TSHR (0.36) HPGDS
SCHEMBL19328330 0.80 HPGDS (0.33) HPGDS
SCHEMBL17802205 0.80 HPGDS (0.33) HPGDS
SCHEMBL11312585 0.80 SLC6A2 (0.33) HPGDS
SCHEMBL9203873 0.80 ELANE (0.36) HPGDS
SCHEMBL9188420 0.80 MEN1 (0.45) NPC1HPGDSEPHX1HTTMEN1
SCHEMBL26087002 0.80 HPGDS (0.33) HPGDS
SCHEMBL18997091 0.80 NPC1 (0.37) NPC1
SCHEMBL5642783 0.78 NPC1 (0.40) NPC1EPHX1HTT
Ethylene Glycol SCHEMBL27888550 0.77 NPC1 (0.32) NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1288280-B1 Use of tertiary alcohols or esters as perfuming ingredients FIRMENICH & CIE (CH) 2007-01-03 EP claimed
US-6720295-B2 COMPOUND CONTAINING CYCLOPENT(EN)YL RING FIRMENICH SA (CH) 2004-04-13 US claimed
US-20030087775-A1 Use of tertiary alcohols or esters as perfuming ingredients FIRMENICH SA (CH) 2003-05-08 US claimed
EP-1288280-A2 Use of tertiary alcohols or esters as perfuming ingredients FIRMENICH SA (CH) 2003-03-05 EP claimed
EP-1288280-B1 Use of tertiary alcohols or esters as perfuming ingredients FIRMENICH & CIE (CH) 2007-01-03 EP disclosed
US-6720295-B2 COMPOUND CONTAINING CYCLOPENT(EN)YL RING FIRMENICH SA (CH) 2004-04-13 US disclosed
US-20030087775-A1 Use of tertiary alcohols or esters as perfuming ingredients FIRMENICH SA (CH) 2003-05-08 US disclosed
EP-1288280-A2 Use of tertiary alcohols or esters as perfuming ingredients FIRMENICH SA (CH) 2003-03-05 EP disclosed